research.funding

Search US federal biomedical research grants via NIH RePORTER. Filter by term (free-text over project title, terms, and abstract), org (funded institution name), pi (principal-investigator name), and/or fiscalYear; page with limit (1-50) and offset. Returns each award with project number, title, fiscal year, award amount (USD), contact PI, organization (name, city, state, country, department), funding agency/institute, and project start/end dates — newest fiscal year first, with a total match count. Data: NIH RePORTER, free and public-domain. Fresh post-training award data agents cannot know; pair with /api/research/org (ROR) and /api/research/author (ORCID). Use for funding landscape research, competitor/lab tracking, and grant-opportunity context.

price

$0.0018 USDC per call

method

GET/api/research/funding

payment

x402 v2 · USDC on Base (EIP-3009) or Solana (SPL transfer)

auth

None. Sign the payment, retry with PAYMENT-SIGNATURE.

tier

Tier 0 — no paid upstream

Parameters

Name	Type	Description
`term`	string	min 2 chars · max 200 chars
`org`	string	min 2 chars · max 200 chars
`pi`	string	min 2 chars · max 120 chars
`fiscalYear`	integer	min 1985 · max 2100
`limit`	integer	min 1 · max 50
`offset`	integer	min 0 · max 14000

Code samples

cURLbash

# 1. Probe with no auth → 402 envelope with PaymentRequirements
curl -sS 'https://2s.io/api/research/funding?term=xx&org=xx&pi=xx&fiscalYear=1985&limit=10&offset=0'

# 2. Sign + retry with PAYMENT-SIGNATURE:
curl -sS 'https://2s.io/api/research/funding?term=xx&org=xx&pi=xx&fiscalYear=1985&limit=10&offset=0' \
  -H 'PAYMENT-SIGNATURE: <base64-json-payload>'

# Or use the canonical runner (handles probe → sign → retry):
#   EVM_PRIVATE_KEY=0x... node --env-file=.env.local \
#     --experimental-strip-types scripts/x402-pay.ts \
#     'https://2s.io/api/research/funding?term=xx&org=xx&pi=xx&fiscalYear=1985&limit=10&offset=0'

TypeScript / Node — @2sio/sdktypescript

import { TwoS } from '@2sio/sdk'

const client = new TwoS({
  privateKey: process.env.EVM_PRIVATE_KEY as `0x${string}`,
})

const result = await client.research.funding({
  "term": "xx",
  "org": "xx",
  "pi": "xx",
  "fiscalYear": 1985,
  "limit": 10,
  "offset": 0
})

console.log('endpoint:', result.endpoint)
console.log('cost:', result.costUsd, 'USDC')
console.log('tx:', result.settlement?.txHash)
console.log('data:', result.data)

Python — 2siopython

import os
from twosio import TwoS

client = TwoS(private_key=os.environ["EVM_PRIVATE_KEY"])

result = client.research.funding(term="xx", org="xx", pi="xx", fiscalYear=1985, limit=10, offset=0)

print("endpoint:", result.endpoint)
print("cost:", result.cost_usd, "USDC")
print("tx:", (result.settlement or {}).get("tx_hash"))
print("data:", result.data)

MCP — Claude Desktop / AgentKit / any MCP hostjson

// 1. Add @2sio/mcp to your MCP host config (Claude Desktop example below).
//    EVM_PRIVATE_KEY funds x402 payments per call.

// claude_desktop_config.json
{
  "mcpServers": {
    "2sio": {
      "command": "npx",
      "args": ["-y", "@2sio/mcp"],
      "env": { "EVM_PRIVATE_KEY": "0x..." }
    }
  }
}

// 2. Once the server is running, agents call this tool via standard MCP:

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "research.funding",
    "arguments": {
      "term": "xx",
      "org": "xx",
      "pi": "xx",
      "fiscalYear": 1985,
      "limit": 10,
      "offset": 0
    }
  }
}

Response

Field	Type	Description
`query`	object
`total`	number
`count`	number
`awards`	array
`sources`	array

Example response datajson

{
  "query": {
    "term": "example",
    "org": "example",
    "pi": "example",
    "fiscalYear": 1,
    "limit": 1,
    "offset": 1
  },
  "total": 1,
  "count": 1,
  "awards": [
    {
      "projectNum": "example",
      "title": "example",
      "fiscalYear": 1,
      "awardAmount": 1,
      "piName": "example",
      "organization": "example",
      "orgCity": "example",
      "orgState": "example",
      "orgCountry": "example",
      "department": "example",
      "agency": "example",
      "agencyName": "example",
      "startDate": "example",
      "endDate": "example"
    }
  ],
  "sources": [
    {
      "provider": "example",
      "url": "example",
      "license": "example"
    }
  ]
}

Discovery

/api/directory — full catalog of every endpoint
/openapi.json — OpenAPI 3.1 spec (per-op x-payment-info, x402Payment security)
/.well-known/x402 — machine-readable service descriptor for x402-aware crawlers
/.well-known/mcp/server-card.json — MCP SEP-1649 server card
/llms.txt — plain-text manifest for LLM ingestion

2s.io is x402-native. Every call is paid per-request from a USDC-funded EVM wallet on Base — no signup, no API keys, no monthly fees. Source code: github.com/2s-io/sdk.