medical.icd10

Verify and search ICD-10-CM diagnosis codes against the official US code set (FY2026, ~98k entries). Pass code (with or without the dot, e.g. E11.9 or E119) to confirm the code exists and list its more-specific child codes, or q to keyword-search code descriptions (e.g. "type 2 diabetes neuropathy"). Optional billable_only=true restricts results to codes valid for claim submission; limit caps results (1-50, default 10). Returns a verified flag, the exact match if any, and matched codes with billable status plus short and long descriptions. Data: CMS/NCHS ICD-10-CM (public domain), refreshed each US fiscal year. Use to confirm diagnosis codes are real and current before placing them in claims, prior authorizations, or clinical documents.

price

$0.0010 USDC per call

method

GET/api/medical/icd10

payment

x402 v2 · USDC on Base (EIP-3009) or Solana (SPL transfer)

auth

None. Sign the payment, retry with PAYMENT-SIGNATURE.

tier

Tier 0 — no paid upstream

Parameters

Name	Type	Description
`code`	string	ICD-10-CM code to verify, with or without the dot (e.g. E11.9 or E119). Returns the exact match plus more-specific child codes. Provide either code or q, not both. min 3 chars · max 9 chars · match ^[A-Za-z][0-9][0-9A-Za-z](\.?[0-9A-Za-z]{0,4})$
`q`	string	Keyword search over official code descriptions (e.g. "type 2 diabetes neuropathy"). Every word must match. Provide either code or q, not both. min 3 chars · max 120 chars
`billable_only`	boolean	When true, only return codes valid for claim submission (excludes category headers).
`limit`	integer	Maximum codes returned (1-50, default 10). min 1 · max 50

Code samples

cURLbash

# 1. Probe with no auth → 402 envelope with PaymentRequirements
curl -sS 'https://2s.io/api/medical/icd10?code=xxx&q=xxx&billable_only=false&limit=1'

# 2. Sign + retry with PAYMENT-SIGNATURE:
curl -sS 'https://2s.io/api/medical/icd10?code=xxx&q=xxx&billable_only=false&limit=1' \
  -H 'PAYMENT-SIGNATURE: <base64-json-payload>'

# Or use the canonical runner (handles probe → sign → retry):
#   EVM_PRIVATE_KEY=0x... node --env-file=.env.local \
#     --experimental-strip-types scripts/x402-pay.ts \
#     'https://2s.io/api/medical/icd10?code=xxx&q=xxx&billable_only=false&limit=1'

TypeScript / Node — @2sio/sdktypescript

import { TwoS } from '@2sio/sdk'

const client = new TwoS({
  privateKey: process.env.EVM_PRIVATE_KEY as `0x${string}`,
})

const result = await client.medical.icd10({
  "code": "xxx",
  "q": "xxx",
  "billable_only": false,
  "limit": 1
})

console.log('endpoint:', result.endpoint)
console.log('cost:', result.costUsd, 'USDC')
console.log('tx:', result.settlement?.txHash)
console.log('data:', result.data)

Python — 2siopython

import os
from twosio import TwoS

client = TwoS(private_key=os.environ["EVM_PRIVATE_KEY"])

result = client.medical.icd10(code="xxx", q="xxx", billable_only=False, limit=1)

print("endpoint:", result.endpoint)
print("cost:", result.cost_usd, "USDC")
print("tx:", (result.settlement or {}).get("tx_hash"))
print("data:", result.data)

MCP — Claude Desktop / AgentKit / any MCP hostjson

// 1. Add @2sio/mcp to your MCP host config (Claude Desktop example below).
//    EVM_PRIVATE_KEY funds x402 payments per call.

// claude_desktop_config.json
{
  "mcpServers": {
    "2sio": {
      "command": "npx",
      "args": ["-y", "@2sio/mcp"],
      "env": { "EVM_PRIVATE_KEY": "0x..." }
    }
  }
}

// 2. Once the server is running, agents call this tool via standard MCP:

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "medical.icd10",
    "arguments": {
      "code": "xxx",
      "q": "xxx",
      "billable_only": false,
      "limit": 1
    }
  }
}

Response

Field	Type	Description
`query`	object
`verified`	boolean	Code mode: true iff the exact code exists in the official set. null in keyword mode.
`exactMatch`	object	The exact code when verified, else null.
`results`	array	Matched codes in official tabular order (code mode: the code + child codes; keyword mode: billable matches first).
`resultCount`	integer
`fiscalYear`	integer	US fiscal year of the loaded code set.
`source`	object

Example response datajson

{
  "query": {
    "code": "example",
    "q": "example",
    "billableOnly": false,
    "limit": 1
  },
  "verified": false,
  "exactMatch": {
    "code": "example",
    "codeDotted": "example",
    "billable": false,
    "shortDescription": "example",
    "longDescription": "example"
  },
  "results": [
    {
      "code": "example",
      "codeDotted": "example",
      "billable": false,
      "shortDescription": "example",
      "longDescription": "example"
    }
  ],
  "resultCount": 1,
  "fiscalYear": 1,
  "source": {
    "provider": "example",
    "license": "example",
    "url": "example"
  }
}

Discovery

/api/directory — full catalog of every endpoint
/openapi.json — OpenAPI 3.1 spec (per-op x-payment-info, x402Payment security)
/.well-known/x402 — machine-readable service descriptor for x402-aware crawlers
/.well-known/mcp/server-card.json — MCP SEP-1649 server card
/llms.txt — plain-text manifest for LLM ingestion

2s.io is x402-native. Every call is paid per-request from a USDC-funded EVM wallet on Base — no signup, no API keys, no monthly fees. Source code: github.com/2s-io/sdk.