medical.drug-status

One-call drug situational awareness. Give a drug name (resolved to a canonical RxCUI via NIH RxNorm), or an exact rxcui or ndc you already hold, and get back: whether it is currently in FDA shortage, any open or recent FDA recalls, and FDA NDC-directory metadata (labeler, DEA schedule, pharmaceutical class, marketing status). Returns a resolved identity block plus hasCurrentShortage / hasOpenRecall booleans and one found/error block per source (shortages, ndc, recalls). Composition of NIH RxNorm + OpenFDA drug-shortages, NDC directory, and recall enforcement — all free, public-domain US government data; each source degrades independently. Point-in-time public records, not medical advice. Use for pharmacy/supply-chain triage, prescribing-support agents, and verifying a drug is real, scheduled, and available before acting.

price

$0.0060 USDC per call

method

GET/api/medical/drug-status

payment

x402 v2 · USDC on Base (EIP-3009) or Solana (SPL transfer)

auth

None. Sign the payment, retry with PAYMENT-SIGNATURE.

tier

Tier 0 — no paid upstream

Parameters

Name	Type	Description
`drug`	string	min 2 chars · max 120 chars
`rxcui`	string	match ^\d{1,9}$
`ndc`	string	min 3 chars · max 20 chars
`limit`	integer	min 1 · max 50

Code samples

cURLbash

# 1. Probe with no auth → 402 envelope with PaymentRequirements
curl -sS 'https://2s.io/api/medical/drug-status?drug=xx&rxcui=12345&ndc=xxx&limit=10'

# 2. Sign + retry with PAYMENT-SIGNATURE:
curl -sS 'https://2s.io/api/medical/drug-status?drug=xx&rxcui=12345&ndc=xxx&limit=10' \
  -H 'PAYMENT-SIGNATURE: <base64-json-payload>'

# Or use the canonical runner (handles probe → sign → retry):
#   EVM_PRIVATE_KEY=0x... node --env-file=.env.local \
#     --experimental-strip-types scripts/x402-pay.ts \
#     'https://2s.io/api/medical/drug-status?drug=xx&rxcui=12345&ndc=xxx&limit=10'

TypeScript / Node — @2sio/sdktypescript

import { TwoS } from '@2sio/sdk'

const client = new TwoS({
  privateKey: process.env.EVM_PRIVATE_KEY as `0x${string}`,
})

const result = await client.medical.drugStatus({
  "drug": "xx",
  "rxcui": "12345",
  "ndc": "xxx",
  "limit": 10
})

console.log('endpoint:', result.endpoint)
console.log('cost:', result.costUsd, 'USDC')
console.log('tx:', result.settlement?.txHash)
console.log('data:', result.data)

Python — 2siopython

import os
from twosio import TwoS

client = TwoS(private_key=os.environ["EVM_PRIVATE_KEY"])

result = client.medical.drug_status(drug="xx", rxcui="12345", ndc="xxx", limit=10)

print("endpoint:", result.endpoint)
print("cost:", result.cost_usd, "USDC")
print("tx:", (result.settlement or {}).get("tx_hash"))
print("data:", result.data)

MCP — Claude Desktop / AgentKit / any MCP hostjson

// 1. Add @2sio/mcp to your MCP host config (Claude Desktop example below).
//    EVM_PRIVATE_KEY funds x402 payments per call.

// claude_desktop_config.json
{
  "mcpServers": {
    "2sio": {
      "command": "npx",
      "args": ["-y", "@2sio/mcp"],
      "env": { "EVM_PRIVATE_KEY": "0x..." }
    }
  }
}

// 2. Once the server is running, agents call this tool via standard MCP:

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "medical.drug-status",
    "arguments": {
      "drug": "xx",
      "rxcui": "12345",
      "ndc": "xxx",
      "limit": 10
    }
  }
}

Response

Field	Type	Description
`query`	object
`resolved`	object
`hasCurrentShortage`	boolean
`hasOpenRecall`	boolean
`shortages`	object
`ndc`	object
`recalls`	object
`sources`	array
`note`	string

Example response datajson

{
  "query": {
    "drug": "example",
    "rxcui": "example",
    "ndc": "example"
  },
  "resolved": {
    "rxcui": "example",
    "name": "example",
    "termType": "example",
    "matchScore": 1
  },
  "hasCurrentShortage": false,
  "hasOpenRecall": false,
  "shortages": {
    "found": false,
    "error": "example",
    "data": {}
  },
  "ndc": {
    "found": false,
    "error": "example",
    "data": {}
  },
  "recalls": {
    "found": false,
    "error": "example",
    "data": {}
  },
  "sources": [
    {
      "provider": "example",
      "url": "example",
      "license": "example"
    }
  ],
  "note": "example"
}

Discovery

/api/directory — full catalog of every endpoint
/openapi.json — OpenAPI 3.1 spec (per-op x-payment-info, x402Payment security)
/.well-known/x402 — machine-readable service descriptor for x402-aware crawlers
/.well-known/mcp/server-card.json — MCP SEP-1649 server card
/llms.txt — plain-text manifest for LLM ingestion

2s.io is x402-native. Every call is paid per-request from a USDC-funded EVM wallet on Base — no signup, no API keys, no monthly fees. Source code: github.com/2s-io/sdk.